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Persons with advanced HIV infection can be treated appropriately. Azithromycin works by stopping the spread of infection and remaining bacteria are killed by the body's immune system or eventually die. Zithromax is an unusual antibiotic in that it stays in the body for quite a long time as it has a prolonged half-life that allows for once a day dosing and also for short-term treatment courses for most infections, Azithromycin is indicated in the treatment of uncomplicated genital infections. Do not follow the full dosage schedule of Zithromax, even if you feel better in a few days.